Store Repatha in the refrigerator between 36°F and 46°F (2°C to 8°C), in the original carton until use to protect it from light. If needed, you can keep it at room temperature for up to 30 days. Always follow the storage instructions that came with your medication.
In the refrigerator
Keep the autoinjector carton in the refrigerator between 36°F and 46°F (2°C to 8°C) until you’re ready to use it.
Keep it in the original carton to protect it from light or physical damage.
Do not freeze Repatha. Don’t use an autoinjector that has been frozen.
Do not shake Repatha at any time.
Keep Repatha and all medicines out of the sight and reach of children.
At room temperature
If needed, for example when you’re traveling, Repatha can be kept at room temperature between 68°F and 77°F (20°C to 25°C) in the original carton for up to 30 days.
Write down the date you took it out of the refrigerator and use it within 30 days.
Throw away Repatha that has been stored at room temperature for more than 30 days: place the autoinjector in a sharps disposal container (see “How do I safely dispose of needles?”).
Do not store the autoinjector in extreme heat or cold. For example, avoid storing it in your vehicle’s glove box or trunk.
Before you inject
Take out the number of autoinjectors you need for your injection and put any unused autoinjectors back in the refrigerator. Wait 30 minutes for the autoinjector to reach room temperature. Let it warm up naturally. Don’t heat it with hot water, a microwave or direct sunlight. Using the autoinjector at room temperature makes sure the full dose is delivered and allows for a more comfortable injection. Don’t use the autoinjector after the expiration date on the label. For the injection steps, see “How do I take Repatha?”
Who to contact
If your Repatha has been frozen, or has been at room temperature for more than 30 days, don’t use it. Contact your pharmacy about a replacement. If your Repatha got too warm, ask your pharmacy whether it’s still OK to use before you use it. The pharmacy handles damaged medication and replacements.
If a replacement means you’ll miss a dose or need a new prescription, or for anything about how you feel on your medication, message your clinician through the chat on your Dashboard. Reply to the most recent message about your prescription.
In an emergency, call 911. If you’re having thoughts of harming yourself, call or text 988.
Sources
This article follows the manufacturer’s storage instructions for Repatha. If you’d like to read them yourself:
Repatha Patient Information, Amgen, revised October 2026
Repatha SureClick autoinjector Instructions for Use, Amgen, revised August 2025 (the instructions are inside the full Repatha labeling PDF, after the Patient Information)
How to take Repatha (Amgen’s injection page), Amgen, updated June 2026
GenMeds checked this article against these documents on October 27, 2026. Your pharmacy’s package insert is always the final word for the medication you were dispensed.